Quote from https://capsule8.com/blog/kernel-configuration-glossary/:

> Significance: High
> 
> This option checks for a stack overrun on calls to schedule(). If the stack
> end location is found to be over written always panic as the content of the
> corrupted region can no longer be trusted. This is to ensure no erroneous
> behaviour occurs which could result in data corruption or a sporadic crash at a
> later stage once the region is examined. The runtime overhead introduced is
> minimal.

In my opinion this can be safely enabled on all architectures.